Grinspan’s syndrome

challenging diagnosis and treatment

Autori

  • Elen de Souza Tolentino Professor, Stomatology and Oral Radiology at UniCesumar and State University of Maringá, PR, Brazil
  • Gustavo Nascimento de Souza Pinto MSc, PhD Student, Department of Oral Diagnosis, Area of Oral Radiology, Piracicaba Dental School, University of Campinas.
  • Helder Fernando Borges Junior Postgraduate Student, State University of Maringá, PR, Brazil
  • Lilian Cristina Vessoni Iwaki Professor, Department of Stomatology and Oral Radiology, State University of Maringá, PR, Brazil.
  • Mariliani Chicarelli da Silva Professor, Department of Stomatology and Oral Radiology, State University of Maringá, PR, Brazil.
  • Vanessa Veltrini Professor, Department of Oral Pathology, State University of Maringá, PR, Brazil.

Parole chiave:

Lichen Planus, Oral, Diabetes Mellitus, Hypertension

Abstract

We present a case of a 52-year old woman with severe and constant pain affecting the tongue and a burning sensation in the mouth. Intraoral examination showed diffuse, erythematous, extremely painful ulcerations especially in the tongue. The diagnostic hypothesis of erosive lichen planus was confirmed in the microscopic exam. The lesions were extremely refractory to the treatment, and the medical history of diabetes mellitus and hypertension support the Grinspan’s syndrome diagnosis. This rare entity is sparsely related, possibly due to the lack of information regarding this triad. This work also lists the reported cases in the literature and speculates if other conditions, as well as anxiety, depression and hepatitis C, play a role in the pathogenesis of this syndrome, enhancing the symptoms.

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Pubblicato

2019-10-09

Come citare

Tolentino, E. de S., Pinto, G. N. de S., Borges Junior, H. F., Iwaki, L. C. V. ., Silva, M. C. da, & Veltrini, V. . (2019). Grinspan’s syndrome: challenging diagnosis and treatment. Arquivo Brasileiro De Odontologia, 14(1), 35–43. Recuperato da https://periodicos.pucminas.br/Arquivobrasileirodontologia/article/view/21412